Programmable microfluidic patterning of protein gradients on hydrogels

Chem Commun (Camb). 2011 Jan 7;47(1):191-3. doi: 10.1039/c0cc02377a. Epub 2010 Sep 8.

Abstract

Computer-controlled hydrodynamic flow focusing was utilized to generate tethered protein gradients of any user-defined shape on the surface of soft synthetic hydrogels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation
  • Hydrodynamics
  • Hydrogels / chemical synthesis
  • Hydrogels / chemistry*
  • Microfluidic Analytical Techniques / instrumentation
  • Microfluidic Analytical Techniques / methods*
  • Molecular Structure
  • Particle Size
  • Polyethylene Glycols / chemistry
  • Proteins / chemistry*
  • Software*
  • Surface Properties

Substances

  • Hydrogels
  • Proteins
  • Polyethylene Glycols