Fibrillar superstructure from extended nanotapes formed by a collagen-stimulating peptide

Chem Commun (Camb). 2010 Dec 28;46(48):9185-7. doi: 10.1039/c0cc03793a. Epub 2010 Oct 29.

Abstract

The nanostructure of a peptide amphiphile in commercial use in anti-wrinkle creams is investigated. The peptide contains a matrikine, collagen-stimulating, pentapeptide sequence. Self-assembly into giant nanotapes is observed and the internal structure was found to comprise bilayers parallel to the flat tape surfaces.

MeSH terms

  • Collagen / drug effects*
  • Cosmetics / chemistry*
  • Humans
  • Molecular Structure
  • Nanostructures / chemistry
  • Peptides / chemistry*
  • Peptides / pharmacology*
  • Surface-Active Agents / chemistry

Substances

  • Cosmetics
  • Peptides
  • Surface-Active Agents
  • Collagen