Septic arthritis caused by Legionella dumoffii in a patient with systemic lupus erythematosus-like disease

M Flendrie; M Jeurissen; M Franssen; D Kwa; C Klaassen; F Vos

doi:10.1128/JCM.00606-10

Septic arthritis caused by Legionella dumoffii in a patient with systemic lupus erythematosus-like disease

J Clin Microbiol. 2011 Feb;49(2):746-9. doi: 10.1128/JCM.00606-10. Epub 2010 Nov 24.

Authors

M Flendrie¹, M Jeurissen, M Franssen, D Kwa, C Klaassen, F Vos

Affiliation

¹ Department of Rheumatology, Sint Maartenskliniek Nijmegen, Hengstdal 3, P.O. Box 9011, 6500 GM, Nijmegen, Netherlands. m.flendrie@flen.nl

Abstract

We describe a patient with systemic lupus erythematosus (SLE)-like disease on immunosuppressive treatment who developed septic arthritis of the knee involving Legionella dumoffii. Cultures initially remained negative. A broad-range 16S PCR using synovial fluid revealed L. dumoffii rRNA genes, a finding that was subsequently confirmed by positive Legionella culture results.

Publication types

Case Reports

MeSH terms

Arthritis, Infectious / microbiology*
DNA, Bacterial / genetics
DNA, Ribosomal / genetics
Female
Humans
Immunocompromised Host
Immunosuppressive Agents / administration & dosage
Immunosuppressive Agents / adverse effects
Legionella / classification
Legionella / genetics
Legionella / isolation & purification*
Legionellosis / diagnosis*
Legionellosis / microbiology
Lupus Erythematosus, Systemic / complications*
Lupus Erythematosus, Systemic / drug therapy
Middle Aged
Polymerase Chain Reaction
RNA, Ribosomal, 16S / genetics

Substances

DNA, Bacterial
DNA, Ribosomal
Immunosuppressive Agents
RNA, Ribosomal, 16S