Shift work is not associated with high blood pressure or prevalence of hypertension

PLoS One. 2010 Dec 14;5(12):e15250. doi: 10.1371/journal.pone.0015250.

Abstract

Background: Working mostly at night has been suggested to be associated with upset of chronobiological rhythms and high blood pressure, but the evidence from epidemiological studies is weak.

Methods: In a cross-sectional survey, we evaluated the association between shift work and blood pressure, pre-hypertension and hypertension. In total, 493 nurses, nurse technicians and assistants, were selected at random in a large general hospital setting. Hypertension was diagnosed by the mean of four automatic blood pressure readings≥140/90 mmHg or use of blood pressure lowering agents, and pre-hypertension by systolic blood pressure≥120-139 or diastolic blood pressure≥80-89 mmHg. Risk factors for hypertension were evaluated by a standardized questionnaire and anthropometric measurements. The association between the shift of work and blood pressure, pre-hypertension and hypertension was explored using univariate and multivariate analyses that controlled for risk factors for hypertension by covariance analysis and modified Poisson regression.

Results: The mean age of the participants was 34.3±9.4 years and 88.2% were women. Night shift workers were older, more frequently married or divorced, and less educated. The prevalence of hypertension in the whole sample was 16%, and 28% had pre-hypertension. Blood pressure (after adjustment for confounding) was not different in day and night shift workers. The prevalence of hypertension and pre-hypertension by shift work was not different in the univariate analysis and after adjustment for confounding (all risk ratios=1.0).

Conclusion: Night shift work did not increase blood pressure and was not associated with hypertension or pre-hypertension in nursing personnel working in a large general hospital.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Blood Pressure
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension / epidemiology*
  • Hypertension / etiology
  • Male
  • Middle Aged
  • Nurses
  • Prevalence
  • Risk Factors
  • Work
  • Work Schedule Tolerance / physiology*