Abstract
We report 13 cases of Naegleria fowleri primary amebic meningoencephalitis in persons in Karachi, Pakistan, who had no history of aquatic activities. Infection likely occurred through ablution with tap water. An increase in primary amebic meningoencephalitis cases may be attributed to rising temperatures, reduced levels of chlorine in potable water, or deteriorating water distribution systems.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Amebiasis / epidemiology
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Amebiasis / parasitology
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Amebiasis / physiopathology
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Animals
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Central Nervous System Protozoal Infections / epidemiology*
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Central Nervous System Protozoal Infections / parasitology
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Central Nervous System Protozoal Infections / physiopathology
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Communicable Diseases, Emerging / epidemiology*
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Communicable Diseases, Emerging / parasitology
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Communicable Diseases, Emerging / physiopathology
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DNA, Protozoan / analysis
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DNA, Protozoan / genetics
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DNA, Protozoan / isolation & purification
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Female
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Fresh Water / parasitology
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Hot Temperature
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Humans
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Male
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Middle Aged
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Naegleria fowleri / genetics
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Naegleria fowleri / isolation & purification
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Naegleria fowleri / pathogenicity*
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Pakistan / epidemiology
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Polymerase Chain Reaction
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Water Supply
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Young Adult