Efficacy of amprolium for the treatment of pathogenic Eimeria species in Boer goat kids

Vet Parasitol. 2011 Jun 10;178(3-4):346-9. doi: 10.1016/j.vetpar.2011.01.028. Epub 2011 Jan 21.

Abstract

This study evaluated the efficacy of two different doses of amprolium in goats heavily infected with pathogenic Eimeria species. Forty Boer goat kids ranging from 3 to 5 months of age with naturally occurring coccidiosis were randomly divided into 2 groups and treated orally with amprolium at doses of 10mg/kg daily for 5 days (n=20) or 50mg/kg daily for 5 days (n=20). The Eimeria oocyst per gram concentrations were significantly reduced on day 7 in the kids that received amprolium at 50mg/kg, however oocyst concentrations were not significantly reduced in goats that received the 10mg/kg dose. Out of 100 Eimeria oocysts identified from a pooled fecal sample, E. christenseni was the most frequently identified (52%) coccidial species present. The results of this trial indicate that amprolium can be an effective treatment for pathogenic Eimeria species in goat kids, however higher and extralabel doses (50mg/kg) should be used.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Amprolium / administration & dosage*
  • Animals
  • Coccidiosis / drug therapy*
  • Coccidiosis / parasitology
  • Coccidiosis / veterinary*
  • Coccidiostats / administration & dosage*
  • Eimeria / growth & development*
  • Feces / parasitology
  • Female
  • Goat Diseases / drug therapy*
  • Goat Diseases / parasitology*
  • Goats
  • Male
  • Parasite Egg Count / veterinary

Substances

  • Coccidiostats
  • Amprolium