Metabolomics and surgical oncology: Potential role for small molecule biomarkers

J Surg Oncol. 2011 Apr;103(5):451-9. doi: 10.1002/jso.21831. Epub 2010 Dec 28.

Abstract

Metabolomics, the newest of the "omics" sciences, has brought much excitement to the field of oncology as a potential new translational tool capable of bringing the molecular world of cancer care to the bedside. While still early in its development, metabolomics could alter the scope and role of surgery in the multidisciplinary treatment of cancer. This review examines potential roles of metabolomics in areas of early cancer detection, personalized therapeutics and tumorigenesis.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism*
  • Colorectal Neoplasms / diagnosis*
  • Colorectal Neoplasms / metabolism*
  • Humans
  • Medical Oncology
  • Metabolomics / methods*
  • Metabolomics / trends
  • Specialties, Surgical

Substances

  • Biomarkers, Tumor