A salt made of 4-N,N-dimethylaminopyridine (DMAP) and saccharin as an efficient recyclable acylation catalyst: a new bridge between heterogeneous and homogeneous catalysis

Norman Lu; Wei-Hsuan Chang; Wen-Han Tu; Chieh-Keng Li

doi:10.1039/c1cc11556a

A salt made of 4-N,N-dimethylaminopyridine (DMAP) and saccharin as an efficient recyclable acylation catalyst: a new bridge between heterogeneous and homogeneous catalysis

Chem Commun (Camb). 2011 Jul 7;47(25):7227-9. doi: 10.1039/c1cc11556a. Epub 2011 May 27.

Authors

Norman Lu¹, Wei-Hsuan Chang, Wen-Han Tu, Chieh-Keng Li

Affiliation

¹ Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei 106, Taiwan. normanlu@ntut.edu.tw

PMID: 21623435
DOI: 10.1039/c1cc11556a

Abstract

Here, we report insights into the new recyclable catalyst 1, (DMAP·saccharin). The DMAP·saccharin-catalysed acylation of alcohols has been successfully carried out more than 8 times. Only 1 mol% of catalyst 1 efficiently promotes acylation with almost equimolar amounts of acid anhydrides, under both base-free and solvent-free conditions.