Evaluating the effectiveness of the response to equine influenza in the Australian outbreak and the potential role of early vaccination

Aust Vet J. 2011 Jul:89 Suppl 1:143-5. doi: 10.1111/j.1751-0813.2011.00769.x.

Abstract

Objective: To use modelling and epidemiological analyses to assess the effectiveness of control strategies employed during the equine influenza outbreak and determine if early vaccination might have had a beneficial effect.

Methods: Transmission of infection was modelled using stochastic, spatial simulation, based on data from 16 regions in New South Wales and Queensland over the first month of the outbreak.

Results: The model accurately represented the spread of infection in both space and time and showed that vaccination strategies would have reduced new infections by ∼60% and reduced the size of the infected area by 8-9%, compared to the non-vaccination baseline.

Conclusion: When used in conjunction with biosecurity measures and movement controls, early vaccination could play an important role in the containment and eradication of equine influenza.

MeSH terms

  • Animals
  • Computer Simulation
  • Disease Outbreaks / prevention & control
  • Disease Outbreaks / veterinary*
  • Horse Diseases / epidemiology
  • Horse Diseases / immunology
  • Horse Diseases / prevention & control*
  • Horse Diseases / transmission
  • Horse Diseases / virology*
  • Horses
  • Influenza A Virus, H3N8 Subtype / immunology*
  • Influenza Vaccines / administration & dosage*
  • Influenza Vaccines / immunology
  • New South Wales / epidemiology
  • Orthomyxoviridae Infections / epidemiology
  • Orthomyxoviridae Infections / immunology
  • Orthomyxoviridae Infections / prevention & control*
  • Orthomyxoviridae Infections / transmission
  • Orthomyxoviridae Infections / veterinary*
  • Queensland / epidemiology
  • Stochastic Processes
  • Vaccination / standards
  • Vaccination / veterinary

Substances

  • Influenza Vaccines