Nanotechnology for therapy and imaging of liver diseases

J Hepatol. 2011 Dec;55(6):1461-6. doi: 10.1016/j.jhep.2011.05.039. Epub 2011 Jul 27.

Abstract

Nanotechnology has been considered for the improved delivery of various therapeutic agents, including drugs and genes. Indeed, liposomes and nanoparticles equipped with homing devices for the targeting of receptors over-expressed on the hepatic tissue have improved the treatment of various liver diseases. In this review, various nanotechnology approaches employed for the treatment/imaging of liver disease, either in preclinical or in clinic are discussed.

Publication types

  • Review

MeSH terms

  • Animals
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / therapy
  • Diagnostic Imaging
  • Drug Delivery Systems
  • Hepatitis / therapy
  • Humans
  • Liver Diseases / diagnosis*
  • Liver Diseases / therapy*
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / therapy
  • Magnetite Nanoparticles
  • Nanotechnology*

Substances

  • Magnetite Nanoparticles