Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae)

Phytochemistry. 2011 Dec;72(17):2244-52. doi: 10.1016/j.phytochem.2011.07.008. Epub 2011 Sep 3.

Abstract

Monoterpenoids (3 and 4), sesquiterpenoid (2), diterpenoid (1) and four phenethyl glucosides (5-8), together with fourteen known compounds, were isolated from the whole herb of Hyssopus cuspidatus. Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C(4) secretion from primary alveolar cells of Wistar rats.

MeSH terms

  • Animals
  • Female
  • Glucosides / chemistry
  • Glucosides / isolation & purification
  • Glucosides / pharmacology*
  • Lamiaceae / chemistry*
  • Leukotriene C4 / metabolism*
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Rats
  • Rats, Wistar
  • Terpenes / chemistry*
  • Terpenes / isolation & purification
  • Terpenes / pharmacology

Substances

  • Glucosides
  • Plant Extracts
  • Terpenes
  • Leukotriene C4