An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate

Org Biomol Chem. 2011 Oct 21;9(20):6927-9. doi: 10.1039/c1ob06248d. Epub 2011 Sep 5.

Abstract

A formal asymmetric synthesis of the antiviral agent (-)-oseltamivir phosphate is achieved using two aldol reactions as key steps.

MeSH terms

  • Molecular Structure
  • Oseltamivir / chemical synthesis*
  • Stereoisomerism

Substances

  • Oseltamivir