In vitro antioxidant activities of sulfated polysaccharide fractions extracted from Corallina officinalis

Yuling Yang; Dan Liu; Jun Wu; Yan Chen; Shusheng Wang

doi:10.1016/j.ijbiomac.2011.08.026

In vitro antioxidant activities of sulfated polysaccharide fractions extracted from Corallina officinalis

Int J Biol Macromol. 2011 Dec 1;49(5):1031-7. doi: 10.1016/j.ijbiomac.2011.08.026. Epub 2011 Sep 1.

Authors

Yuling Yang¹, Dan Liu, Jun Wu, Yan Chen, Shusheng Wang

Affiliation

¹ School of Life Science, Anhui University, Feixi Street, Hefei 230039, PR China.

PMID: 21896282
DOI: 10.1016/j.ijbiomac.2011.08.026

Abstract

Sulfated polysaccharides (F1, F2) from seaweed Corallina officinalis were isolated through anion-exchange column chromatography. Their chemical characteristics were determined by GC, HPLC, FT-IR and UV spectra. F1 and F2 contained only two monosaccharides, namely galactose and xylose. The antioxidant activities of F1, F2 and the de-sulfated polysaccharides (DF-1, DF-2) in vitro were investigated, including hydroxyl radicals scavenging effect, superoxide radical scavenging capacity, DPPH radical activity and reducing power. As expected, antioxidant assay showed that the two sulfated polysaccharide fractions (F1, F2) possessed considerable antioxidant properties and had more excellent abilities than de-sulfated polysaccharides (DF-1, DF-2).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biphenyl Compounds / antagonists & inhibitors
Biphenyl Compounds / metabolism
Chemistry, Pharmaceutical / methods*
Chromatography, High Pressure Liquid
Chromatography, Ion Exchange
Food Preservation / methods*
Free Radical Scavengers / chemistry
Free Radical Scavengers / isolation & purification
Free Radical Scavengers / pharmacology*
Free Radicals / antagonists & inhibitors
Free Radicals / metabolism
Galactose / chemistry
Galactose / metabolism
Humans
Hydroxyl Radical / antagonists & inhibitors
Hydroxyl Radical / metabolism
Oxidation-Reduction / drug effects
Picrates / antagonists & inhibitors
Picrates / metabolism
Polysaccharides / chemistry
Polysaccharides / isolation & purification
Polysaccharides / pharmacology*
Rhodophyta / chemistry*
Seaweed / chemistry*
Solutions
Spectroscopy, Fourier Transform Infrared
Sulfates / chemistry
Sulfates / metabolism*
Superoxides / antagonists & inhibitors
Superoxides / metabolism
Xylose / chemistry
Xylose / metabolism

Substances

Biphenyl Compounds
Free Radical Scavengers
Free Radicals
Picrates
Polysaccharides
Solutions
Sulfates
Superoxides
Hydroxyl Radical
Xylose
1,1-diphenyl-2-picrylhydrazyl
Galactose