Abstract
A new fluorescent sensor L1 based on coumarin was synthesized. It shows high sensitivity and selectivity toward Cu(2+) in aqueous solution. The complexation mode and corresponding quenching mechanism were elucidated by ESI-MS and DFT calculations. In addition, biological imaging studies have demonstrated that L1 can detect Cu(2+) in living cells.
MeSH terms
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Coordination Complexes / chemical synthesis
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Coordination Complexes / chemistry*
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Copper / chemistry*
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Coumarins / chemistry*
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Crystallography, X-Ray
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Fluorescent Dyes / chemistry*
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Hep G2 Cells
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Humans
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Hydrazones / chemistry*
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Microscopy, Confocal*
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Molecular Conformation
Substances
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Coordination Complexes
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Coumarins
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Fluorescent Dyes
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Hydrazones
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Copper
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coumarin