[Pharmacotherapy for preventing calcium containing stone formation]

Clin Calcium. 2011 Oct;21(10):1530-4.
[Article in Japanese]

Abstract

Many urinary tract stones consist of calcium, and has high relapse rate. Accordingly, it is very important to prevent calcium-containing stone formation. This paper describes about effects and mechanisms for Xanthine oxidase inhibitor, citrate formulation, magnesium formulation, thiazides, vitamin B(6), extract of Quercus salicina Blume and chorei-to (medical herb) . Recent new drugs and the elucidation of new metabolic pathways may lead to the development of prevention of urolithiasis.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Allopurinol / pharmacology*
  • Allopurinol / therapeutic use*
  • Animals
  • Calcium / metabolism*
  • Citrates / pharmacology
  • Citrates / therapeutic use
  • Drugs, Chinese Herbal / pharmacology
  • Drugs, Chinese Herbal / therapeutic use
  • Humans
  • Magnesium Compounds / pharmacology
  • Magnesium Compounds / therapeutic use
  • Phytotherapy
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Secondary Prevention
  • Sodium Chloride Symporter Inhibitors / pharmacology
  • Sodium Chloride Symporter Inhibitors / therapeutic use
  • Urinary Calculi / drug therapy*
  • Urinary Calculi / metabolism
  • Urinary Calculi / prevention & control*
  • Vitamin B 6 / pharmacology
  • Vitamin B 6 / therapeutic use
  • Xanthine Oxidase / antagonists & inhibitors

Substances

  • Citrates
  • Drugs, Chinese Herbal
  • Magnesium Compounds
  • Plant Extracts
  • Sodium Chloride Symporter Inhibitors
  • choreito
  • Allopurinol
  • Vitamin B 6
  • Xanthine Oxidase
  • Calcium