Selective formation of six-membered oxa- and carbocycles by the In(III)-activated ring closure of acetylenic substrates

Org Lett. 2011 Nov 4;13(21):5893-5. doi: 10.1021/ol202621g. Epub 2011 Oct 12.

Abstract

Fifteen examples are disclosed of efficient In(III)-catalyzed six-membered ring closure leading to bi-, tri-, and tetracyclic products.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylene / chemistry*
  • Carbon / chemistry*
  • Catalysis
  • Cyclization
  • Indium / chemistry*
  • Macrocyclic Compounds / chemical synthesis
  • Molecular Structure
  • Oxygen / chemistry*
  • Stereoisomerism

Substances

  • Macrocyclic Compounds
  • Indium
  • Carbon
  • Acetylene
  • Oxygen