Drug delivery by electropulsation: Recent developments in oncology

J Teissié; J M Escoffre; A Paganin; S Chabot; E Bellard; L Wasungu; M P Rols; M Golzio

doi:10.1016/j.ijpharm.2011.09.038

Drug delivery by electropulsation: Recent developments in oncology

Int J Pharm. 2012 Feb 14;423(1):3-6. doi: 10.1016/j.ijpharm.2011.09.038. Epub 2011 Oct 1.

Authors

J Teissié¹, J M Escoffre, A Paganin, S Chabot, E Bellard, L Wasungu, M P Rols, M Golzio

Affiliation

¹ CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, F-31077 Toulouse, France. justin.teissie@ipbs.fr

PMID: 21996516
DOI: 10.1016/j.ijpharm.2011.09.038

Abstract

Electro-permeabilisation allows the free access of polar compounds to the cytoplasm by a reversible alteration of the cell membrane. It is now used in clinics for the eradication of cutaneous solid tumors. New developments predict its future applications for other anti-cancer treatments.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Drug Delivery Systems / methods*
Electrochemotherapy / adverse effects
Electrochemotherapy / methods*
Humans
Metal Nanoparticles / administration & dosage
Metal Nanoparticles / therapeutic use
Neoplasms / drug therapy*
Photochemotherapy / methods