Electrocardiographic signals and swarm-based support vector machine for hypoglycemia detection

Ann Biomed Eng. 2012 Apr;40(4):934-45. doi: 10.1007/s10439-011-0446-7. Epub 2011 Oct 20.

Abstract

Cardiac arrhythmia relating to hypoglycemia is suggested as a cause of death in diabetic patients. This article introduces electrocardiographic (ECG) parameters for artificially induced hypoglycemia detection. In addition, a hybrid technique of swarm-based support vector machine (SVM) is introduced for hypoglycemia detection using the ECG parameters as inputs. In this technique, a particle swarm optimization (PSO) is proposed to optimize the SVM to detect hypoglycemia. In an experiment using medical data of patients with Type 1 diabetes, the introduced ECG parameters show significant contributions to the performance of the hypoglycemia detection and the proposed detection technique performs well in terms of sensitivity and specificity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arrhythmias, Cardiac / physiopathology*
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Electrocardiography / methods*
  • Humans
  • Hypoglycemia / diagnosis*
  • Hypoglycemia / physiopathology*
  • Sensitivity and Specificity