Second-generation platelet concentrate (PRF) as a pulpotomy medicament in a permanent molar with pulpitis: a case report

Int Endod J. 2012 Jan;45(1):105-12. doi: 10.1111/j.1365-2591.2011.01973.x. Epub 2011 Nov 14.

Abstract

Aim: To discuss the clinical and radiographic success of a pulpotomy with second-generation platelet concentrate (PRF), in a human mature permanent molar tooth.

Summary: A 19-year-old female patient reported to the Department of Conservative Dentistry and Endodontics with established pulpitis in tooth 36. The tooth had a carious pulp exposure, with a history of lingering pain. After isolation, caries removal and pulp exposure, pulpotomy with PRF was performed and a permanent restoration was placed immediately. At the first recall (+1 day), no postoperative pain was reported. At 6, 12, 18 and 22 months recall, the tooth responded positively to pulp sensibility tests, and radiographic examination revealed a normal periodontal ligament space. Positive results of this case imply the need for more studies with larger sample sizes and a longer recall period to justify the use of this novel material for the treatment of pulpitis in human permanent molar teeth.

Key learning points: Pulpotomy with PRF could be an alternate treatment to mineral trioxide aggregate or other materials in mature permanent teeth with pulpitis.

Publication types

  • Case Reports

MeSH terms

  • Aluminum Compounds / therapeutic use
  • Blood Platelets / physiology*
  • Calcium Compounds / therapeutic use
  • Dental Pulp Exposure / therapy
  • Dental Pulp Test
  • Dental Restoration, Permanent / methods
  • Drug Combinations
  • Female
  • Fibrin / therapeutic use*
  • Follow-Up Studies
  • Glass Ionomer Cements / chemistry
  • Humans
  • Molar / diagnostic imaging
  • Molar / pathology*
  • Oxides / therapeutic use
  • Periodontal Ligament / diagnostic imaging
  • Pulpitis / therapy
  • Pulpotomy / methods*
  • Radiography, Bitewing
  • Root Canal Filling Materials / therapeutic use
  • Silicates / therapeutic use
  • Young Adult

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Drug Combinations
  • Glass Ionomer Cements
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • Fibrin