Abstract
The modified Hodge test has an excellent sensitivity for detecting enterobacterial isolates producing Ambler class A (KPC) and class D (OXA-48) carbapenemases. Its sensitivity is low for NDM-1 producers (50%) but is increased to 85.7% by adding ZnSO(4) (100 μg/ml) in the culture medium. However, this test has a low specificity and is time-consuming.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Proteins / analysis*
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Bacteriological Techniques / methods*
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Culture Media / chemistry
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Enterobacteriaceae / enzymology*
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Sensitivity and Specificity
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Zinc Sulfate / metabolism
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beta-Lactamases / analysis*
Substances
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Bacterial Proteins
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Culture Media
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Zinc Sulfate
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beta-Lactamases
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carbapenemase