Rapid fluorescent detection of neurogenin3 by CdTe quantum dot aggregation

Yue Yuan; Jia Zhang; Gaolin Liang; Xiurong Yang

doi:10.1039/c2an16166d

Rapid fluorescent detection of neurogenin3 by CdTe quantum dot aggregation

Analyst. 2012 Apr 21;137(8):1775-8. doi: 10.1039/c2an16166d. Epub 2012 Mar 12.

Authors

Yue Yuan¹, Jia Zhang, Gaolin Liang, Xiurong Yang

Affiliation

¹ State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China.

PMID: 22407238
DOI: 10.1039/c2an16166d

Abstract

Here we report a facile immunoassay for detecting a synthetic peptide fragment of neurogenin3 (amino acid sequence: SKQRRSRRKKANDRERNRMH) by harnessing the aggregation-dependent fluorescence property of antibody-conjugated CdTe quantum dots in the presence of the target.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Basic Helix-Loop-Helix Transcription Factors / analysis*
Basic Helix-Loop-Helix Transcription Factors / chemistry
Cadmium Compounds / chemistry*
Immunoassay
Molecular Sequence Data
Nerve Tissue Proteins / analysis*
Nerve Tissue Proteins / chemistry
Quantum Dots*
Spectrometry, Fluorescence / methods*
Tellurium / chemistry*

Substances

Basic Helix-Loop-Helix Transcription Factors
Cadmium Compounds
NEUROG3 protein, human
Nerve Tissue Proteins
Tellurium
cadmium telluride