Comparison study of biomimetic strontium-doped calcium phosphate coatings by electrochemical deposition and air plasma spray: morphology, composition and bioactive performance

J Mater Sci Mater Med. 2012 Oct;23(10):2359-68. doi: 10.1007/s10856-012-4633-3. Epub 2012 Apr 18.

Abstract

In this study, strontium-doped calcium phosphate coatings were deposited by electrochemical deposition and plasma spray under different process parameters to achieve various coating morphologies. The coating composition was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy while the cytocompatibility and bioactivity of the strontium-doped calcium phosphate coatings were evaluated using bone cell culture using MC3T3-E1 osteoblast-like cells. The addition of strontium leads to enhanced proliferation suggesting the possible benefits of strontium incorporation in calcium phosphate coatings. The morphology and composition of deposited coatings showed a strong influence on the growth of cells.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Air
  • Biomimetics*
  • Calcium Phosphates / chemistry*
  • Electrochemical Techniques*
  • Microscopy, Electron, Scanning
  • Strontium / chemistry*
  • X-Ray Diffraction

Substances

  • Calcium Phosphates
  • calcium phosphate
  • Strontium