Acute glomerulonephritis in dengue haemorrhagic fever in the absence of shock, sepsis, haemolysis or rhabdomyolysis

Paediatr Int Child Health. 2012 Aug;32(3):161-3. doi: 10.1179/2046905512Y.0000000001.

Abstract

Renal damage in dengue haemorrhagic fever (DHF) has been reported in association with shock, haemolysis, rhabdomyolysis and sepsis. This report describes acute glomerulonephritis with DHF without the above-mentioned complications. A 3-year-old boy presented with fever, vomiting and oliguria. He had hypertension, deranged renal function and low serum complement (C3), and urine microscopy showed red blood cells and granular casts. The IgM and IgG ELISA (rapid test) for dengue virus were positive. He was managed with maintenance fluids, intravenous furosemide and supportive care. He made an uneventful recovery and was discharged 7 days after admission.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Viral / blood*
  • Child, Preschool
  • Dengue Virus / immunology*
  • Diuretics / administration & dosage
  • Enzyme-Linked Immunosorbent Assay
  • Fluid Therapy
  • Furosemide / administration & dosage
  • Glomerulonephritis / diagnosis*
  • Glomerulonephritis / drug therapy
  • Glomerulonephritis / pathology*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Male
  • Microscopy
  • Severe Dengue / complications
  • Severe Dengue / diagnosis*
  • Severe Dengue / pathology*
  • Severe Dengue / therapy
  • Treatment Outcome
  • Urine / cytology

Substances

  • Antibodies, Viral
  • Diuretics
  • Immunoglobulin G
  • Immunoglobulin M
  • Furosemide