The aging epigenome: DNA methylation from the cradle to the grave

Genome Biol. 2012 Jul 30;13(7):165. doi: 10.1186/gb4033.

Abstract

Whole-genome methylation analysis of newborns and centenarians reveals widespread epigenetic alterations, and provides new insight into age-related methylation pattern changes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Aging / genetics*
  • DNA Methylation*
  • Epigenesis, Genetic
  • Epigenomics / methods*
  • Genome, Human
  • Humans
  • Infant, Newborn