Oral and extra-oral taste perception

Kurumi Yamamoto; Yoshiro Ishimaru

doi:10.1016/j.semcdb.2012.08.005

Oral and extra-oral taste perception

Semin Cell Dev Biol. 2013 Mar;24(3):240-6. doi: 10.1016/j.semcdb.2012.08.005. Epub 2012 Sep 2.

Authors

Kurumi Yamamoto¹, Yoshiro Ishimaru

Affiliation

¹ Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

PMID: 22963927
DOI: 10.1016/j.semcdb.2012.08.005

Abstract

Of the five basic taste qualities, the molecular mechanisms underlying sweet, bitter, and umami (savory) taste perception have been extensively elucidated, including the taste receptors and downstream signal transduction molecules. Recent studies have revealed that these taste-related molecules play important roles not only in the oral cavity but also in a variety of tissues including the respiratory tract, stomach, intestines, pancreas, liver, kidney, testes, and brain. This review covers the current knowledge regarding the physiological roles of taste-related molecules in the oral and extra-oral tissues.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cell Lineage
Humans
Mouth / physiology*
Receptors, Cell Surface / metabolism
Signal Transduction
Taste
Taste Perception*

Substances

Receptors, Cell Surface