A smart nanofiber web that captures and releases cells

Young-Jin Kim; Mitsuhiro Ebara; Takao Aoyagi

doi:10.1002/anie.201204139

A smart nanofiber web that captures and releases cells

Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10537-41. doi: 10.1002/anie.201204139. Epub 2012 Sep 18.

Authors

Young-Jin Kim¹, Mitsuhiro Ebara, Takao Aoyagi

Affiliation

¹ Materials and Science Engineering, Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan.

PMID: 22991233
DOI: 10.1002/anie.201204139

Abstract

Caught in a web: Photo-cross-linkable temperature-responsive polymer-based nanofiber webs have been synthesized that have the ability to capture, encapsulate, and release cells by dynamically transforming the fibrous structure into hydrogel-like structures by wrapping, swelling, and deswelling processes in response to external temperature changes (see picture).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acrylamides / chemistry
Benzophenones / chemistry
Cytological Techniques / instrumentation*
Cytological Techniques / methods
Fibroblasts / cytology*
Humans
Hydrogels / chemistry*
Models, Theoretical
Nanofibers / chemistry*
Photochemical Processes
Temperature
Tensile Strength

Substances

Acrylamides
Benzophenones
Hydrogels
benzophenone
N-isopropylacrylamide