Synthesis and evaluation of antioxidant and antibacterial behavior of CuO nanoparticles

Colloids Surf B Biointerfaces. 2013 Jan 1:101:430-3. doi: 10.1016/j.colsurfb.2012.07.002. Epub 2012 Jul 25.

Abstract

CuO nanoparticles were synthesized by thermal decomposition methods and characterized by UV-visible spectroscopy, XRD and TEM analysis. The resultant particles are nearly spherical and particle size is in the range of 15-30 nm. The antioxidant behavior of synthesized CuO nanoparticles was evaluated by scavenging free radicals of 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH). The free radical scavenging activity of CuO nanoparticles was monitored by UV-visible spectrophotometry. The antibacterial activity of CuO nanoparticles was tested against different bacterial strains. CuO nanoparticles showed efficient antioxidant activity and bactericidal effect against Eschericia coli and Pseudomonas aeruginosa.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / chemistry*
  • Antioxidants / chemical synthesis
  • Antioxidants / chemistry*
  • Bacteria / drug effects
  • Biphenyl Compounds
  • Copper / chemistry*
  • Free Radical Scavengers / chemistry
  • Free Radicals
  • Microbial Sensitivity Tests
  • Microscopy, Electron, Transmission
  • Nanoparticles
  • Particle Size
  • Picrates
  • Spectrophotometry, Ultraviolet

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Free Radicals
  • Picrates
  • Copper
  • 1,1-diphenyl-2-picrylhydrazyl
  • cupric oxide