Abstract
Staphylococcus aureus clonal complex 398 (CC398) isolates colonize livestock and can spread to human contacts. Genetic analysis of isolates epidemiologically associated with human-to-human, but not livestock, transmission in multiple countries and continents identified a common clade that was negative for tet(M) and positive for bacteriophage 3. Another group of human-to-human-transmitted isolates belonged to the common livestock-associated clade but had acquired a unique 7 bacteriophage.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Bacterial Proteins / genetics
-
Bacteriophages / genetics
-
Cluster Analysis
-
DNA, Bacterial / genetics
-
Humans
-
Microarray Analysis
-
Staphylococcal Infections / microbiology*
-
Staphylococcal Infections / transmission*
-
Staphylococcal Infections / veterinary
-
Staphylococcus aureus / classification
-
Staphylococcus aureus / genetics
-
Staphylococcus aureus / pathogenicity*
-
Staphylococcus aureus / virology
-
Swine
Substances
-
Bacterial Proteins
-
DNA, Bacterial
-
Tet M resistance protein, Bacteria