Uniform polypyrrole nanoparticles with high photothermal conversion efficiency for photothermal ablation of cancer cells

Adv Mater. 2013 Feb 6;25(5):777-82. doi: 10.1002/adma.201202211. Epub 2012 Nov 12.

Abstract

Uniform polypyrrole (PPy) nanoparticles are fabricated from a facile one-step aqueous dispersion polymerization. Owing to their high photothermal conversion efficiency and photostability compared with the well-known Au nanorods, as well as their good colloidal stability and biocompatibility, the resulting PPy nanoparticles can used as a novel promising photothermal ablation coupling agent for targeted treatment of cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • HeLa Cells
  • Humans
  • Hyperthermia, Induced / methods*
  • Materials Testing
  • Nanoparticles / therapeutic use*
  • Neoplasms, Experimental / pathology*
  • Neoplasms, Experimental / therapy*
  • Photosensitizing Agents / therapeutic use
  • Phototherapy / methods*
  • Polymers / therapeutic use*
  • Pyrroles / therapeutic use*
  • Treatment Outcome

Substances

  • Photosensitizing Agents
  • Polymers
  • Pyrroles
  • polypyrrole