Human-to-human transmission of severe fever with thrombocytopenia syndrome bunyavirus through contact with infectious blood

J Infect Dis. 2013 Mar 1;207(5):736-9. doi: 10.1093/infdis/jis748. Epub 2012 Dec 6.

Abstract

We investigated an outbreak of severe fever with thrombocytopenia syndrome (SFTS) that occurred during May and June 2010, to identify the mode of transmission. Contact with the index patient's blood was significantly associated with development of SFTS (P = .01, by the χ(2) test for linear trend); the frequency of contact with the index patient's blood increased the risk of SFTS in a dose-response manner (P = .03, by the χ(2) test for linear trend). We concluded that human-to-human transmission caused this cluster of cases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood / virology*
  • Bunyaviridae Infections / transmission*
  • Bunyaviridae Infections / virology
  • Cohort Studies
  • Disease Outbreaks*
  • Disease Transmission, Infectious*
  • Humans
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Phlebovirus / isolation & purification*
  • RNA, Viral / genetics
  • Retrospective Studies
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • RNA, Viral

Associated data

  • GENBANK/HQ642766
  • GENBANK/HQ642767
  • GENBANK/HQ642768
  • GENBANK/JF682773
  • GENBANK/JF682774
  • GENBANK/JF682775
  • GENBANK/JF682776
  • GENBANK/JF682777
  • GENBANK/JF682778