Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane: remarkable effect of palladium nanoparticles

Xiujuan Feng; Anle Sun; Sheng Zhang; Xiaoqiang Yu; Ming Bao

doi:10.1021/ol303135e

Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane: remarkable effect of palladium nanoparticles

Org Lett. 2013 Jan 4;15(1):108-11. doi: 10.1021/ol303135e. Epub 2012 Dec 18.

Authors

Xiujuan Feng¹, Anle Sun, Sheng Zhang, Xiaoqiang Yu, Ming Bao

Affiliation

¹ State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China. fengxiujuan@dlut.edu.cn

PMID: 23249213
DOI: 10.1021/ol303135e

Abstract

Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane was successfully conducted to produce benzyl but-3-enoates in satisfactory to good yields. The carboxylative coupling reaction occurred smoothly under mild conditions in the presence of palladium nanoparticles in tetrahydrofuran.