The relationship between nut consumption and lipid profile among the Iranian adult population; Isfahan Healthy Heart Program

Eur J Clin Nutr. 2013 Apr;67(4):385-9. doi: 10.1038/ejcn.2013.21. Epub 2013 Feb 20.

Abstract

Background/objective: The study was carried out to assess the relationship between nut consumption and lipid profile among Iranian adults.

Subject/methods: The study was based on data from the Isfahan Healthy Heart Program across three counties in central Iran in 2007. A cross-sectional survey of 9660 randomly selected adults aged ≥ 19 years were chosen based on sex, age and settlement distributions in each community. Nutritional behaviors were assessed by validated qualitative 48-item food frequency questionnaires, which covered regular intakes of four types of nuts: walnuts, almonds, pistachios and hazelnuts. Analysis of covariance and logistic regression tests were utilized to determine odds ratio (OR) 95% confidence interval of hyperlipidemia according to nut consumption patterns in unadjusted and three-adjusted models.

Results: The results showed a significant link between high nut consumption and lower total cholesterol, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) levels and apo B/apo A ratio (P<0.05) in female subjects and lower TG, LDL-C and apoB/apoA ratio in male subjects (P<0.05). The frequency of nut consumption was inversely associated with dyslipidemia, especially for those who had consumed nuts ≥ 4 times weekly (0.67 (0.57-0.79)). After adjusting for sex, age and other potential confounders, ORs increased enormously. Except for low apo A and high LDL-C, more frequent nut consumption (4 ≤ times per week) had a significant inverse effect on other dyslipidemia risk factors in all four models.

Conclusions: We concluded that frequent consumption of nuts, particularly ≥ 4 times a week, may result in lower dyslipidemia occurrences and may exert cardioprotective effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Apolipoproteins A / blood
  • Apolipoproteins B / blood
  • Cholesterol, HDL / blood*
  • Cross-Sectional Studies
  • Feeding Behavior*
  • Female
  • Humans
  • Hyperlipidemias / blood
  • Iran
  • Lipoproteins, LDL / blood*
  • Logistic Models
  • Male
  • Middle Aged
  • Nutrition Assessment
  • Nuts*
  • Odds Ratio
  • Risk Factors
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • Triglycerides / blood*
  • White People
  • Young Adult

Substances

  • Apolipoproteins A
  • Apolipoproteins B
  • Cholesterol, HDL
  • Lipoproteins, LDL
  • Triglycerides