Abstract
Four new nardosinane-type sesquiterpenoids, parathyrsoidins A-D (1-4) were isolated from the soft coral Paralemnalia thyrsoides. The structures of parathyrsoidins A-D (1-4) were determined by extensive spectral analysis and their cytotoxicity against selected cancer cell lines as well as antiviral activity against human cytomegalovirus (HCMV) were evaluated in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anthozoa / chemistry*
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology
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Biological Factors / chemistry*
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Biological Factors / pharmacology
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Cell Line, Tumor
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Cytomegalovirus / drug effects
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Humans
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Molecular Structure
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Sesquiterpenes / chemistry*
Substances
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Antiviral Agents
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Biological Factors
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Sesquiterpenes