Quinoline: A versatile heterocyclic

Saudi Pharm J. 2013 Jan;21(1):1-12. doi: 10.1016/j.jsps.2012.03.002. Epub 2012 Mar 29.

Abstract

Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for the synthesis of this ring. The article aims at highlighting these very diversities of the ring.

Keywords: Biological activity; Quinoline; Synthesis.