Abstract
The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.25 μg/ml; micafungin, 1 μg/ml; voriconazole, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 8 μg/ml; amphotericin B, 16 μg/ml; fluconazole, 64 μg/ml.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amphotericin B / pharmacology
-
Antifungal Agents / pharmacology*
-
Caspofungin
-
Echinocandins / pharmacology
-
Exophiala / drug effects*
-
Fluconazole / pharmacology
-
Itraconazole / pharmacology
-
Lipopeptides / pharmacology
-
Micafungin
-
Microbial Sensitivity Tests
-
Nitriles / pharmacology
-
Pyridines / pharmacology
-
Pyrimidines / pharmacology
-
Triazoles / pharmacology
-
Voriconazole
Substances
-
Antifungal Agents
-
Echinocandins
-
Lipopeptides
-
Nitriles
-
Pyridines
-
Pyrimidines
-
Triazoles
-
Itraconazole
-
isavuconazole
-
posaconazole
-
Amphotericin B
-
Fluconazole
-
Caspofungin
-
Voriconazole
-
Micafungin