Tumor ablation: common modalities and general practices

Tech Vasc Interv Radiol. 2013 Dec;16(4):192-200. doi: 10.1053/j.tvir.2013.08.002.

Abstract

Tumor ablation is a minimally invasive technique that is commonly used in the treatment of tumors of the liver, kidney, bone, and lung. During tumor ablation, thermal energy is used to heat or cool tissue to cytotoxic levels (less than -40°C or more than 60°C). An additional technique is being developed that targets the permeability of the cell membrane and is ostensibly nonthermal. Within the classification of tumor ablation, there are several modalities used worldwide: radiofrequency, microwave, laser, high-intensity focused ultrasound, cryoablation, and irreversible electroporation. Each technique, although similar in purpose, has specific and optimal indications. This review serves to discuss general principles and technique, reviews each modality, and discusses modality selection.

Keywords: HIFU; IRE; Microwave; cryoablation; laser; radiofrequency.

Publication types

  • Review

MeSH terms

  • Ablation Techniques* / adverse effects
  • Ablation Techniques* / instrumentation
  • Ablation Techniques* / methods
  • Animals
  • Humans
  • Neoplasms / diagnosis
  • Neoplasms / surgery*
  • Patient Selection
  • Predictive Value of Tests
  • Risk Factors
  • Surgery, Computer-Assisted* / adverse effects
  • Surgery, Computer-Assisted* / instrumentation
  • Surgery, Computer-Assisted* / methods
  • Treatment Outcome