•First case report of successfully treating severe paclitaxel and docetaxel hypersensitivity reaction with nab-paclitaxel•We demonstrated that nab-paclitaxel is a safe taxane chemotherapy treatment option for patients who could not tolerate paclitaxel or docetaxel.
Keywords: Abraxane; Docetaxel; Hypersensitivity reaction; Nab-paclitaxel; Paclitaxel; Taxol.