Structures of acylated sucroses from the flower buds of Prunus mume

J Nat Med. 2014 Jul;68(3):481-7. doi: 10.1007/s11418-014-0818-z. Epub 2014 Feb 16.

Abstract

Seven new acylated sucroses, mumeoses P-V, were isolated from the flower buds of Prunus mume, cultivated in Zhejiang province, China. Their chemical structures were elucidated on the basis of chemical and physicochemical evidence. Moreover, mumeoses C, D, and R, were shown to substantially inhibit aldose reductase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Reductase / antagonists & inhibitors*
  • Animals
  • China
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Flowers / chemistry
  • Lens, Crystalline / enzymology
  • Prunus / chemistry*
  • Rats
  • Sucrose / analogs & derivatives*
  • Sucrose / chemistry
  • Sucrose / pharmacology

Substances

  • Enzyme Inhibitors
  • Sucrose
  • Aldehyde Reductase