GM-CSF along with IL-4 but not alone is indispensable for the differentiation of human dendritic cells from monocytes

Sahana Holla; Meenu Sharma; Janakiraman Vani; Srini V Kaveri; Kithiganahalli N Balaji; Jagadeesh Bayry

doi:10.1016/j.jaci.2014.02.021

GM-CSF along with IL-4 but not alone is indispensable for the differentiation of human dendritic cells from monocytes

J Allergy Clin Immunol. 2014 May;133(5):1500-2, 1502.e1. doi: 10.1016/j.jaci.2014.02.021. Epub 2014 Apr 1.

Authors

Sahana Holla¹, Meenu Sharma², Janakiraman Vani¹, Srini V Kaveri³, Kithiganahalli N Balaji⁴, Jagadeesh Bayry⁵

Affiliations

¹ Unité 1138, Institut National de la Santé et de la Recherche Médicale, Paris, France; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
² Unité 1138, Institut National de la Santé et de la Recherche Médicale, Paris, France; Université de Technologie de Compiègne, Compiègne, France.
³ Unité 1138, Institut National de la Santé et de la Recherche Médicale, Paris, France; Centre de Recherche des Cordeliers, Equipe 16-Immunopathology and Therapeutic Immunointervention, Université Pierre et Marie Curie - Paris 6, Paris, France; Université Paris Descartes, Paris, France; International Associated Laboratory IMPACT (Institut National de la Santé et de la Recherche Médicale, France - Indian Council of Medical Research, India), National Institute of Immunohaematology, Mumbai, India.
⁴ Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India. Electronic address: balaji@mcbl.iisc.ernet.in.
⁵ Unité 1138, Institut National de la Santé et de la Recherche Médicale, Paris, France; Centre de Recherche des Cordeliers, Equipe 16-Immunopathology and Therapeutic Immunointervention, Université Pierre et Marie Curie - Paris 6, Paris, France; Université Paris Descartes, Paris, France; International Associated Laboratory IMPACT (Institut National de la Santé et de la Recherche Médicale, France - Indian Council of Medical Research, India), National Institute of Immunohaematology, Mumbai, India. Electronic address: jagadeesh.bayry@crc.jussieu.fr.

PMID: 24698325
DOI: 10.1016/j.jaci.2014.02.021

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Dendritic Cells / immunology*
Hypersensitivity / immunology*
Interleukin-4 / metabolism*
Th1 Cells / immunology*
Th2 Cells / immunology*

Substances

Interleukin-4