A fluorescence ratiometric chemosensor for Fe³⁺ based on TBET and its application in living cells

Cuicui Wang; Di Zhang; Xiaoyan Huang; Peigang Ding; Zhenji Wang; Yufen Zhao; Yong Ye

doi:10.1016/j.talanta.2014.03.073

A fluorescence ratiometric chemosensor for Fe³⁺ based on TBET and its application in living cells

Talanta. 2014 Oct:128:69-74. doi: 10.1016/j.talanta.2014.03.073. Epub 2014 Apr 23.

Authors

Cuicui Wang¹, Di Zhang¹, Xiaoyan Huang², Peigang Ding¹, Zhenji Wang², Yufen Zhao³, Yong Ye⁴

Affiliations

¹ Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052, China.
² School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, China.
³ Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052, China; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
⁴ Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052, China; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. Electronic address: yeyong03@tsinghua.org.cn.

PMID: 25059132
DOI: 10.1016/j.talanta.2014.03.073

Abstract

Based on a through bond energy transfer (TBET) between rhodamine and naphthalimide fluorophores, a fluorescent ratiometric chemosensor L was designed and prepared for highly selective detection of Fe(3+) in aqueous solution and in living EC109 cells. These significant changes in the fluorescence color could be used for naked-eye detection. The reversibility established the potential of the probe as chemosensor for Fe(3+) detection.

Keywords: Fe(3+); Fluorescent chemosensor; Naphthalimide; Rhodamine; TBET.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Color
Energy Transfer
Ferric Compounds / analysis*
Ferric Compounds / chemistry
Fluorescence*
Fluorescent Dyes / chemistry*
Humans
Hydrogen-Ion Concentration
Molecular Structure
Naphthalimides / chemistry*
Reproducibility of Results
Rhodamines / chemistry*
Spectrometry, Fluorescence / methods

Substances

Ferric Compounds
Fluorescent Dyes
Naphthalimides
Rhodamines