dsDNA-specific fluorescent copper nanoparticles as a "green" nano-dye for polymerization-mediated biochemical analysis

Zhihe Qing; Taiping Qing; Zhengui Mao; Xiaoxiao He; Kemin Wang; Zhen Zou; Hui Shi; Dinggeng He

doi:10.1039/c4cc05101g

dsDNA-specific fluorescent copper nanoparticles as a "green" nano-dye for polymerization-mediated biochemical analysis

Chem Commun (Camb). 2014 Oct 28;50(84):12746-8. doi: 10.1039/c4cc05101g.

Authors

Zhihe Qing¹, Taiping Qing, Zhengui Mao, Xiaoxiao He, Kemin Wang, Zhen Zou, Hui Shi, Dinggeng He

Affiliation

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China. kmwang@hnu.edu.cn xiaoxiaohe@hnu.edu.cn.

PMID: 25204899
DOI: 10.1039/c4cc05101g

Abstract

Here we exploit dsDNA-specific fluorescent copper nanoparticles (CuNPs) as a "green" nano-dye for polymerization-mediated biochemical analysis. Good feasibility and universality are demonstrated through detecting three model targets (polymerase, mercury ion and nucleic acid).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Copper / chemistry*
DNA / analysis
DNA / chemistry*
DNA-Directed DNA Polymerase / analysis
Fluorescent Dyes / chemistry*
Green Chemistry Technology
Ions / chemistry
Mercury / analysis
Metal Nanoparticles / chemistry*
Nucleic Acid Hybridization
Polymerization
Spectrometry, Fluorescence

Substances

Fluorescent Dyes
Ions
Copper
DNA
DNA-Directed DNA Polymerase
Mercury