Secondhand smoke exposure within semi-open air cafes and tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) concentrations among nonsmoking employees

Int J Occup Med Environ Health. 2014 Oct;27(5):875-81. doi: 10.2478/s13382-014-0294-4. Epub 2014 Sep 12.

Abstract

Objectives: Secondhand smoke (SHS) is a defined occupational hazard. The association though between SHS exposure in semi-open air venues and tobacco specific carcinogen uptake is an area of debate.

Material and methods: A cross sectional survey of 49 semi-open air cafes in Athens, Greece was performed during the summer of 2008, prior to the adoption of the national smoke free legislation. All venues had at least 1 entire wall open to allow for free air exchange. Indoor concentrations of particulate matter smaller than 2.5 microns (PM2.5) attributable to SHS were assessed during a work shift, while 1 non-smoking employee responsible for indoor and outdoor table service from each venue provided a post work shift urine sample for analysis of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

Results: Post work shift NNAL concentrations were correlated with work shift PM2.5 concentrations attributable to SHS (r = 0.376, p = 0.0076). Urinary NNAL concentrations among employees increased by 9.5%, per 10 μg/m(3) increase in PM2.5 concentrations attributable to SHS after controlling for the time of day and day of week.

Conclusions: These results indicate that the commonly proposed practice of maintaining open sliding walls as a means of free air exchange does not lead to the elimination of employee exposure to tobacco specific carcinogens attributable to workplace SHS.

MeSH terms

  • Adult
  • Air Pollutants / analysis*
  • Cross-Sectional Studies
  • Female
  • Greece
  • Humans
  • Male
  • Middle Aged
  • Nitrosamines / analysis*
  • Occupational Exposure / adverse effects*
  • Occupational Exposure / analysis*
  • Particulate Matter / adverse effects
  • Particulate Matter / analysis
  • Pyridines / analysis*
  • Restaurants*
  • Tobacco Smoke Pollution / analysis*

Substances

  • Air Pollutants
  • Nitrosamines
  • Particulate Matter
  • Pyridines
  • Tobacco Smoke Pollution
  • 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol