Virus capture and destruction by label-free graphene oxide for detection and disinfection applications

Zhiyong Song; Xiaoyu Wang; Genxing Zhu; Qinggong Nian; Hangyu Zhou; Dong Yang; Chengfeng Qin; Ruikang Tang

doi:10.1002/smll.201401706

Virus capture and destruction by label-free graphene oxide for detection and disinfection applications

Small. 2015 Mar;11(9-10):1171-6. doi: 10.1002/smll.201401706. Epub 2014 Oct 6.

Authors

Zhiyong Song¹, Xiaoyu Wang, Genxing Zhu, Qinggong Nian, Hangyu Zhou, Dong Yang, Chengfeng Qin, Ruikang Tang

Affiliation

¹ Center for Biomaterials and Bioparthways, Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, 310027, P. R. China.

PMID: 25285820
DOI: 10.1002/smll.201401706

Abstract

Graphene oxide (GO) can efficiently capture viruses, destroy their surface proteins, and extract viral RNA in an aqueous environment by using the superficial bioreduction of GO. It follows from these phenomena that GO is an excellent nanomaterial for the high-throughput detection and disinfection of viruses, demonstrating its great potential for the prevention of environmental infections.

Keywords: capture; detection; disinfection; graphene oxide; viruses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antiviral Agents / chemistry
Biosensing Techniques
Disinfection / methods*
Graphite / chemistry*
Hot Temperature
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Nanostructures / chemistry
Nanotechnology / methods*
Oxides / chemistry*
RNA, Viral / chemistry*
Spectrophotometry, Ultraviolet
Spectroscopy, Fourier Transform Infrared
Surface Properties
Water / chemistry

Substances

Antiviral Agents
Oxides
RNA, Viral
Water
Graphite