Sleep, sleep disturbance, and fertility in women

Sleep Med Rev. 2015 Aug:22:78-87. doi: 10.1016/j.smrv.2014.10.005. Epub 2014 Oct 18.

Abstract

Sleep and sleep disturbances are increasingly recognized as determinants of women's health and well-being, particularly in the context of the menstrual cycle, pregnancy, and menopause. At present, however, little is known about whether fertility is affected by sleep quantity and quality. That is, to what degree, and by what mechanisms, do sleep and/or its disturbances affect fertility? The purpose of this review is to synthesize what is known about sleep disturbances in relation to reproductive capacity. A model is provided, whereby stress, sleep dysregulation, and circadian misalignment are delineated for their potential relevance to infertility. Ultimately, if it is the case that sleep disturbance is associated with infertility, new avenues for clinical intervention may be possible.

Keywords: Circadian; Infertility; Insomnia; Reproductive health; Reproductive hormones; Sleep; Sleep disturbance; Women's health.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Female
  • Fertility / physiology*
  • Humans
  • Infertility, Female / etiology*
  • Infertility, Female / physiopathology
  • Pregnancy
  • Sleep / physiology*
  • Sleep Wake Disorders / complications*
  • Sleep Wake Disorders / physiopathology