Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation

Mohan S Maddur; Jamma Trinath; Magalie Rabin; Francis Bolgert; Moneger Guy; Jean-Michel Vallat; Laurent Magy; Kithiganahalli N Balaji; Srini V Kaveri; Jagadeesh Bayry

doi:10.1038/cmi.2014.117

Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation

Cell Mol Immunol. 2015 Sep;12(5):650-2. doi: 10.1038/cmi.2014.117. Epub 2014 Dec 8.

Authors

Mohan S Maddur^{1

2

3

4}, Jamma Trinath^{1

5}, Magalie Rabin^{1

2

3

6}, Francis Bolgert⁷, Moneger Guy⁷, Jean-Michel Vallat⁶, Laurent Magy⁶, Kithiganahalli N Balaji⁵, Srini V Kaveri^{1

2

3

4

8}, Jagadeesh Bayry^{1

2

3

4

8}

Affiliations

¹ Institut National de la Santé et de la Recherche Médicale, Paris, France.
² Centre de Recherche des Cordeliers, Equipe - Immunopathology and Therapeutic Immunointervention, Paris, France.
³ Sorbonne Universités - UPMC Univ Paris 6, Paris, France.
⁴ Université Paris Descartes, Paris, France.
⁵ Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
⁶ Centre de Référence 'Neuropathies Périphériques Rares' et Service de Neurologie, Hôpital Universitaire Limoges, Limoges, France.
⁷ Réanimation Neurologique, Neurologie 1, Hôpital de la Pitié-Salpêtrière, Paris, France.
⁸ International Associated Laboratory IMPACT (Institut National de la Santé et de la Recherche Médicale, France - Indian Council of Medical Research, India), National Institute of Immunohaematology, Mumbai, India.

No abstract available

MeSH terms

Aged
Aged, 80 and over
Autoimmune Diseases / blood*
Autoimmune Diseases / immunology*
Cell Proliferation / drug effects
Dinoprostone / blood*
Female
Humans
Immunoglobulins, Intravenous / immunology*
Immunoglobulins, Intravenous / pharmacology
Male
Middle Aged
T-Lymphocytes, Regulatory / cytology*
T-Lymphocytes, Regulatory / drug effects
T-Lymphocytes, Regulatory / immunology*

Substances

Immunoglobulins, Intravenous
Dinoprostone