Stimulated mass enhancement strategy-based highly sensitive detection of a protein in serum using quartz crystal microbalance technique

Rashida Akter; Bongjin Jeong; Md Aminur Rahman

doi:10.1039/c4an01555j

Stimulated mass enhancement strategy-based highly sensitive detection of a protein in serum using quartz crystal microbalance technique

Analyst. 2015 Feb 21;140(4):995-8. doi: 10.1039/c4an01555j.

Authors

Rashida Akter¹, Bongjin Jeong, Md Aminur Rahman

Affiliation

¹ Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, South Korea. marahman@cnu.ac.kr.

PMID: 25502120
DOI: 10.1039/c4an01555j

Abstract

A stimulated mass enhancement strategy based on enormous biocatalytic precipitation of 4-chloro-1-naphthol using magnetic bead-supported horseradish peroxidase and glucose oxidase bienzymes was developed for the highly sensitive detection of interleukin-6 in serum using a quartz crystal microbalance technique.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Biosensing Techniques
Enzymes, Immobilized / metabolism
Glucose Oxidase / metabolism
Horseradish Peroxidase / metabolism
Humans
Interleukin-6 / blood*
Limit of Detection
Magnetics / methods
Naphthols / metabolism
Quartz Crystal Microbalance Techniques / methods*

Substances

Enzymes, Immobilized
Interleukin-6
Naphthols
4-chloro-1-naphthol
Glucose Oxidase
Horseradish Peroxidase