Childhood allergic asthma is associated with increased IL-13 and FOXP3 histone acetylation

J Allergy Clin Immunol. 2015 Jul;136(1):200-2. doi: 10.1016/j.jaci.2015.01.027. Epub 2015 Mar 11.

Authors

Hani Harb¹, Diana Raedler², Nikolaus Ballenberger², Andreas Böck², Dörthe A Kesper¹, Harald Renz¹, Bianca Schaub³

Affiliations

¹ Institute of Laboratory Medicine, Pathobiochemistry and Molecular Diagnostics, Philipps University, Marburg, Germany.
² Department of Pulmonary and Allergy, University Children's Hospital Munich, LMU, Munich, Germany.
³ Department of Pulmonary and Allergy, University Children's Hospital Munich, LMU, Munich, Germany; German Center for Lung Research (DZL), Munich, Germany. Electronic address: Bianca.Schaub@med.uni-muenchen.de.

PMID: 25769912
DOI: 10.1016/j.jaci.2015.01.027

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acetylation
Adolescent
Asthma / immunology*
Epigenesis, Genetic / immunology
Female
Forkhead Transcription Factors / genetics
Forkhead Transcription Factors / metabolism*
Histones / metabolism*
Humans
Hypersensitivity / immunology*
Interleukin-13 / genetics
Interleukin-13 / metabolism*
Male
T-Lymphocyte Subsets / immunology*
Th1-Th2 Balance
Th2 Cells / immunology*

Substances

FOXP3 protein, human
Forkhead Transcription Factors
Histones
Interleukin-13