Injectable and mechanically robust 4-arm PPO-PEO/graphene oxide composite hydrogels for biomedical applications

Chem Commun (Camb). 2015 May 25;51(42):8876-9. doi: 10.1039/c5cc02511g.

Abstract

Graphene-based nanomaterials with different oxidation degrees were incorporated into Tetronic-tyramine (Tet-TA) hydrogels via enzymatic cross-linking. The molecular oxidation of graphene in combination with amphiphilic Tet-TA significantly improved the water dispersibility of graphene oxide (GO), resulting in a significant reinforcement of Tet-TA/GO composite hydrogels that can be used as an injectable biomaterial platform.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3T3 Cells
  • Animals
  • Biocompatible Materials / administration & dosage
  • Biocompatible Materials / chemical synthesis
  • Biocompatible Materials / chemistry*
  • Biomedical Research
  • Graphite / chemistry*
  • Hydrogels / administration & dosage*
  • Hydrogels / chemical synthesis
  • Hydrogels / chemistry*
  • Injections
  • Mice
  • Oxides / chemistry*
  • Polyethylene Glycols / chemistry*
  • Polymers / chemistry*
  • Propylene Glycols / chemistry*
  • Tyramine / chemistry

Substances

  • Biocompatible Materials
  • Hydrogels
  • Oxides
  • Polymers
  • Propylene Glycols
  • polypropylene glycol
  • Polyethylene Glycols
  • Graphite
  • Tyramine