Organized sports participation and the association with injury in paediatric patients with haemophilia

Haemophilia. 2015 Jul;21(4):538-42. doi: 10.1111/hae.12696. Epub 2015 Apr 30.

Abstract

Introduction: With the wide availability of factor and the routine use of prophylaxis boys with haemophilia are now able to participate in regular physical activity, including organized sports. Current guidelines vary regarding specific recommendations for sports participation and concerns remain regarding safety.

Aim: To determine if participation in organized sports is associated with an increased risk for injury in paediatric subjects with haemophilia.

Methods: Retrospective single-centre cohort study from January 1, 2008 to December 31, 2010 in male subjects ages 10-18 years with a factor VIII (FVIII) or FIX level <40%. The number of injuries per subject and participation in organized sports was recorded.

Results: 48 male subjects with a mean age of 14.3 ± 2.6 years (range: 10-18.8) were included; 64.6% (31/48) FVIII deficiency, 54.2% (26/48) severe haemophilia, 18.8% (9/48) moderate and 27.1% (13/48) mild. The majority [62.5% (30/48)] of subjects participated in at least one season of organized sport. There were 77 injuries in 36/48 (75%) subjects. The mean number of injuries per subject was 1.6 ± 1.5. There was no statistical difference in the mean number of injuries (P = 0.44) or target joint formation (P = 0.52) between the subjects who participated in organized sports compared to those who did not.

Conclusion: In this study, participation in organized sports by boys with haemophilia, ages 10-18 years, is common and not associated with an increased number of injuries or the development of a target joint. As injuries occurred equally in both groups, concerted efforts should be directed at reducing injuries in all patients.

Keywords: haemarthrosis; haemophilia; paediatric; prophylaxis; risk of injury; sports participation.

MeSH terms

  • Adolescent
  • Body Mass Index
  • Child
  • Cohort Studies
  • Factor IX / analysis
  • Factor VIII / analysis
  • Hemophilia A / physiopathology*
  • Humans
  • Male
  • Retrospective Studies
  • Risk
  • Severity of Illness Index
  • Sports*
  • Wounds and Injuries

Substances

  • Factor VIII
  • Factor IX