This communication describes the fabrication of Pt/CeO2 nanotube@SiO2 core-shell catalysts applied to highly efficient water-gas shift reaction, where the initial CO conversion is 30.2% at 250 °C. Pt/CeO2 nanotube@SiO2 core-shell catalysts show outstanding thermal stability, even after accelerated aging under reaction conditions at 450 °C for 6 h, and the morphology is also unchanged after thermal treatment at 800 °C.